MOTS-C 10mg

MOTS-c is a 16-amino acid peptide encoded entirely within the mitochondrial genome — a discovery (Cell Metabolism, 2015) that revealed mitochondria as active endocrine organs. Circulating MOTS-c declines with age and correlates with metabolic health. In animal studies, exogenous MOTS-c reverses insulin resistance, promotes fatty acid oxidation, and extends median lifespan in aged murine models.

• Mitochondrial origin — the only known peptide encoded in the mitochondrial genome.
• Exercise-mimetic effects — activates AMPK in skeletal muscle, promoting glucose uptake and fatty acid oxidation without physical exertion.
• Insulin sensitivity restoration — significant improvement in insulin signalling and glucose tolerance in aged research models.
• Longevity and lifespan — chronic administration extends median lifespan and healthspan in aged mice.
• Age-dependent decline — falling MOTS-c with age makes it a key biomarker for mitochondrial ageing research.

⚠️ For research use only. Not for human or animal consumption. Store at −20°C. Reconstitute with Bacteriostatic Water.