NAD+ 500mg

NAD+ (Nicotinamide Adenine Dinucleotide) is central to over 500 enzymatic reactions, including the sirtuin deacylases (SIRT1–7), PARP DNA-repair enzymes, and CD38 hydrolase. NAD+ concentrations decline ~50% between youth and middle age, correlating strongly with reduced mitochondrial function, DNA-repair capacity, and increased chronic inflammation. Our 500mg large-dose format is among the largest single-vial doses available from a Canadian research supplier.

• Sirtuin activation — obligate cosubstrate for all seven sirtuins regulating mitochondrial biogenesis and epigenetic remodelling.
• DNA repair pathway — PARP1 and PARP2 consume NAD+ during DNA break repair; restoring NAD+ enhances repair efficiency in aged models.
• Mitochondrial function restoration — restores membrane potential, respiration rate, and ATP production to near-youthful levels in aged animals.
• Anti-inflammaging — NAD+ restoration suppresses NF-κB and inflammatory cytokines in aged models.
• 500mg high-dose format — one of the largest single-vial NAD+ doses from a Canadian research supplier.

⚠️ For research use only. Not for human or animal consumption. Store at −20°C. Reconstitute with Bacteriostatic Water.